BDBM50261964 2-(2-((5-chloro-1H-indol-3-yl)methyl)-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl)-1-methyl-1H-imidazole-4-sulfonamide::CHEMBL466771

SMILES: Cn1cc(nc1-c1n(Cc2c[nH]c3ccc(Cl)cc23)nc2n(CC3CC3)c(=O)n(C)c(=O)c12)S(N)(=O)=O

InChI Key: InChIKey=IJDURAWPESRNLL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261964   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate racemase (Helicobacter pylori)	BDBM50261964 (2-(2-((5-chloro-1H-indol-3-yl)methyl)-7-(cycloprop...) Show SMILES Cn1cc(nc1-c1n(Cc2c[nH]c3ccc(Cl)cc23)nc2n(CC3CC3)c(=O)n(C)c(=O)c12)S(N)(=O)=O |(-4.37,-43.05,;-2.83,-43.05,;-1.93,-41.81,;-.47,-42.28,;-.47,-43.81,;-1.93,-44.3,;-2.4,-45.76,;-1.49,-47.01,;.05,-47.01,;.82,-48.34,;.2,-49.75,;1.34,-50.78,;2.67,-50.01,;4.13,-50.48,;5.27,-49.45,;4.95,-47.95,;6.09,-46.91,;3.49,-47.48,;2.36,-48.5,;-2.4,-48.27,;-3.88,-47.79,;-5.22,-48.55,;-5.22,-50.09,;-6.56,-50.86,;-8.09,-50.86,;-7.33,-52.2,;-6.55,-47.78,;-7.89,-48.55,;-6.55,-46.24,;-7.89,-45.47,;-5.22,-45.46,;-5.22,-43.92,;-3.88,-46.24,;.77,-41.37,;2.1,-40.59,;-.07,-40.08,;1.62,-42.65,)| Show InChI InChI=1S/C23H23ClN8O4S/c1-29-11-17(37(25,35)36)27-21(29)19-18-20(31(9-12-3-4-12)23(34)30(2)22(18)33)28-32(19)10-13-8-26-16-6-5-14(24)7-15(13)16/h5-8,11-12,26H,3-4,9-10H2,1-2H3,(H2,25,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori MurI				Bioorg Med Chem Lett 18: 4716-22 (2008) Article DOI: 10.1016/j.bmcl.2008.06.092 BindingDB Entry DOI: 10.7270/Q2N29WSP
					More data for this Ligand-Target Pair