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BDBM50262015 4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonamide::CHEMBL445517

SMILES: Cc1ccccc1-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=PJTGGTHTXKATBS-UHFFFAOYSA-N

Data: 4 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262015   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50262015
PNG
(4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Show SMILES Cc1ccccc1-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H14N4O2S/c1-11-4-2-3-5-14(11)15-10-19(18-17-15)12-6-8-13(9-7-12)22(16,20)21/h2-10H,1H3,(H2,16,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.70n/an/an/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of human cloned CA2 by CO2 hydration assay


Bioorg Med Chem Lett 18: 4624-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.010
More data for this
Ligand-Target Pair
Carbonic Anhydrase VA


(Homo sapiens (Human))
BDBM50262015
PNG
(4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Show SMILES Cc1ccccc1-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H14N4O2S/c1-11-4-2-3-5-14(11)15-10-19(18-17-15)12-6-8-13(9-7-12)22(16,20)21/h2-10H,1H3,(H2,16,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
9.30n/an/an/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay


Bioorg Med Chem Lett 18: 4624-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.010
More data for this
Ligand-Target Pair
Carbonic Anhydrase VB


(Homo sapiens (Human))
BDBM50262015
PNG
(4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Show SMILES Cc1ccccc1-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H14N4O2S/c1-11-4-2-3-5-14(11)15-10-19(18-17-15)12-6-8-13(9-7-12)22(16,20)21/h2-10H,1H3,(H2,16,20,21)
Reactome pathway
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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
11.4n/an/an/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA5B by CO2 hydration assay


Bioorg Med Chem Lett 18: 4624-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.010
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM50262015
PNG
(4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)
Show SMILES Cc1ccccc1-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C15H14N4O2S/c1-11-4-2-3-5-14(11)15-10-19(18-17-15)12-6-8-13(9-7-12)22(16,20)21/h2-10H,1H3,(H2,16,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.00E+3n/an/an/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of human cloned CA1 by CO2 hydration assay


Bioorg Med Chem Lett 18: 4624-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.010
More data for this
Ligand-Target Pair