BDBM50262067 4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzenesulfonamide::CHEMBL468367

SMILES: NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1

InChI Key: InChIKey=IJWQBNAFHFXHGD-UHFFFAOYSA-N

Data: 4 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50262067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic Anhydrase VB (Homo sapiens (Human))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human recombinant CA5B by CO2 hydration assay				Bioorg Med Chem Lett 18: 4624-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0
					More data for this Ligand-Target Pair
Carbonic Anhydrase VA (Homo sapiens (Human))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human recombinant CA5A by CO2 hydration assay				Bioorg Med Chem Lett 18: 4624-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human cloned CA2 by CO2 hydration assay				Bioorg Med Chem Lett 18: 4624-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of human cloned CA1 by CO2 hydration assay				Bioorg Med Chem Lett 18: 4624-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.010 BindingDB Entry DOI: 10.7270/Q2959JF0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by fluorescence assay				Bioorg Med Chem 21: 4288-95 (2013) Article DOI: 10.1016/j.bmc.2013.04.074 BindingDB Entry DOI: 10.7270/Q2DV1NTZ
					More data for this Ligand-Target Pair
Prostaglandin E synthase/G/H synthase 2 (Homo sapiens (Human))	BDBM50262067 (4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 by fluorescence assay				Bioorg Med Chem 21: 4288-95 (2013) Article DOI: 10.1016/j.bmc.2013.04.074 BindingDB Entry DOI: 10.7270/Q2DV1NTZ
					More data for this Ligand-Target Pair