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SMILES: COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2cc(Cl)ccc12

InChI Key: InChIKey=HPPXMLLJSBWQRL-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262081   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bone morphogenetic protein 4


(Homo sapiens (Human))		BDBM50262081
PNG
(7-chloro-4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyri...)
Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2cc(Cl)ccc12
Show InChI InChI=1S/C22H15ClN4O/c1-28-17-5-2-14(3-6-17)15-11-25-22-20(12-26-27(22)13-15)18-8-9-24-21-10-16(23)4-7-19(18)21/h2-13H,1H3
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

B.MOAD
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PC sid
UniChem

Similars
Article
PubMed
n/an/a 500n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA

Bioorg Med Chem Lett 18: 4388-92 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.052
BindingDB Entry DOI: 10.7270/Q2BR8S0V
More data for this
Ligand-Target Pair