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BDBM50262509 1-(4-chloro-3-(trifluoromethyl)phenyl)-4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidine::CHEMBL478204

SMILES: Fc1ccc(-c2noc(n2)C2CCN(CC2)c2ccc(Cl)c(c2)C(F)(F)F)c(Cl)c1

InChI Key: InChIKey=ILTVKWITCXQNDJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262509   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))		BDBM50262509
PNG
(1-(4-chloro-3-(trifluoromethyl)phenyl)-4-(3-(2-chl...)
Show SMILES Fc1ccc(-c2noc(n2)C2CCN(CC2)c2ccc(Cl)c(c2)C(F)(F)F)c(Cl)c1
Show InChI InChI=1S/C20H15Cl2F4N3O/c21-16-4-2-13(10-15(16)20(24,25)26)29-7-5-11(6-8-29)19-27-18(28-30-19)14-3-1-12(23)9-17(14)22/h1-4,9-11H,5-8H2
PDB

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n/an/an/an/a 376n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP binding

Bioorg Med Chem Lett 18: 4267-74 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.096
BindingDB Entry DOI: 10.7270/Q21C1WQ8
More data for this
Ligand-Target Pair