BDBM50262585 2-Methyl-3-[4-({3-[(2R)-2-methyl-1-pyrrolidinyl]propyl}oxy)phenyl]-4(3H)-quinazolinone::CHEMBL477361

SMILES: C[C@@H]1CCCN1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=MXIVVCAWALSKFR-QGZVFWFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50262585 (2-Methyl-3-[4-({3-[(2R)-2-methyl-1-pyrrolidinyl]pr...) Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O |r| Show InChI InChI=1S/C23H27N3O2/c1-17-7-5-14-25(17)15-6-16-28-20-12-10-19(11-13-20)26-18(2)24-22-9-4-3-8-21(22)23(26)27/h3-4,8-13,17H,5-7,14-16H2,1-2H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthalenyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]meth...				J Med Chem 51: 4780-9 (2008) Article DOI: 10.1021/jm8003834 BindingDB Entry DOI: 10.7270/Q2FQ9WFW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50262585 (2-Methyl-3-[4-({3-[(2R)-2-methyl-1-pyrrolidinyl]pr...) Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O |r| Show InChI InChI=1S/C23H27N3O2/c1-17-7-5-14-25(17)15-6-16-28-20-12-10-19(11-13-20)26-18(2)24-22-9-4-3-8-21(22)23(26)27/h3-4,8-13,17H,5-7,14-16H2,1-2H3/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells				J Med Chem 51: 4780-9 (2008) Article DOI: 10.1021/jm8003834 BindingDB Entry DOI: 10.7270/Q2FQ9WFW
					More data for this Ligand-Target Pair