BindingDB logo
myBDB logout

null

SMILES: CC1CCCCN1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=VHZWOLIOEMDWAI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262643   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50262643
PNG
(2-Methyl-3-(4-{[3-(2-methyl-1-piperidinyl)propyl]o...)
Show SMILES CC1CCCCN1CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O
Show InChI InChI=1S/C24H29N3O2/c1-18-8-5-6-15-26(18)16-7-17-29-21-13-11-20(12-14-21)27-19(2)25-23-10-4-3-9-22(23)24(27)28/h3-4,9-14,18H,5-8,15-17H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 11n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells

J Med Chem 51: 4780-9 (2008)


Article DOI: 10.1021/jm8003834
BindingDB Entry DOI: 10.7270/Q2FQ9WFW
More data for this
Ligand-Target Pair