BDBM50262712 3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic acid::CHEMBL444116
SMILES: OC(=O)c1cccc(NC(=O)c2cccc3-c4ccccc4C(=O)c23)c1
InChI Key: InChIKey=ASDYJRQOOWNXSU-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calmodulin-sensitive adenylate cyclase (Bacillus anthracis) | BDBM50262712 (3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis edema factor-induced cAMP secretion in mouse RAW264.7 cells after 4 hrs by ELISA | Bioorg Med Chem 16: 7225-33 (2008) Article DOI: 10.1016/j.bmc.2008.06.036 BindingDB Entry DOI: 10.7270/Q2R2116M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calmodulin-sensitive adenylate cyclase (Bacillus anthracis) | BDBM50262712 (3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UTMB Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis edema toxin-mediated cAMP production in mouse RAW264.7 cells after 4 hrs by ELISA | Bioorg Med Chem 20: 368-76 (2012) Article DOI: 10.1016/j.bmc.2011.10.091 BindingDB Entry DOI: 10.7270/Q2PK0K15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calmodulin-sensitive adenylate cyclase (Bacillus anthracis) | BDBM50262712 (3-[(9-oxo-9Hfluorene-1-carbonyl)-amino]-benzoic ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Medical Branch Curated by ChEMBL | Assay Description Inhibition of Bacillus anthracis edema factor-induced cytotoxicity in mouse RAW264.7 cells assessed as LDH release after 4 hrs | Bioorg Med Chem 16: 7225-33 (2008) Article DOI: 10.1016/j.bmc.2008.06.036 BindingDB Entry DOI: 10.7270/Q2R2116M | |||||||||||
More data for this Ligand-Target Pair |