BDBM50262782 5'-Butyrylamino-2'-methyl-biphenyl-4-carboxylic acid cyclopropylmethyl-amide::CHEMBL476533

SMILES: CCCC(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=GAOYNJWKQDRPHM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50262782 (5'-Butyrylamino-2'-methyl-biphenyl-4-carboxylic ac...) Show SMILES CCCC(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C22H26N2O2/c1-3-4-21(25)24-19-12-5-15(2)20(13-19)17-8-10-18(11-9-17)22(26)23-14-16-6-7-16/h5,8-13,16H,3-4,6-7,14H2,1-2H3,(H,23,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50262782 (5'-Butyrylamino-2'-methyl-biphenyl-4-carboxylic ac...) Show SMILES CCCC(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C22H26N2O2/c1-3-4-21(25)24-19-12-5-15(2)20(13-19)17-8-10-18(11-9-17)22(26)23-14-16-6-7-16/h5,8-13,16H,3-4,6-7,14H2,1-2H3,(H,23,26)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair