BDBM50262816 (4-(isoquinolin-3-yl)piperazin-1-yl)(1-(3-methoxyphenyl)-2-p-tolyl-1H-imidazol-4-yl)methanone::CHEMBL515161

SMILES: COc1cccc(c1)-n1cc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1cc2ccccc2cn1

InChI Key: InChIKey=CCFUQIBZCDKHQD-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50262816 ((4-(isoquinolin-3-yl)piperazin-1-yl)(1-(3-methoxyp...) Show SMILES COc1cccc(c1)-n1cc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1cc2ccccc2cn1 Show InChI InChI=1S/C31H29N5O2/c1-22-10-12-23(13-11-22)30-33-28(21-36(30)26-8-5-9-27(19-26)38-2)31(37)35-16-14-34(15-17-35)29-18-24-6-3-4-7-25(24)20-32-29/h3-13,18-21H,14-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50262816 ((4-(isoquinolin-3-yl)piperazin-1-yl)(1-(3-methoxyp...) Show SMILES COc1cccc(c1)-n1cc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1cc2ccccc2cn1 Show InChI InChI=1S/C31H29N5O2/c1-22-10-12-23(13-11-22)30-33-28(21-36(30)26-8-5-9-27(19-26)38-2)31(37)35-16-14-34(15-17-35)29-18-24-6-3-4-7-25(24)20-32-29/h3-13,18-21H,14-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.40	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity against human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
					More data for this Ligand-Target Pair