null

SMILES: Cc1ccc(NC(=O)c2ccno2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=DEGRMENUSQEWHH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50262868 (CHEMBL476543 | Isoxazole-5-carboxylic acid [4'-(cy...) Show SMILES Cc1ccc(NC(=O)c2ccno2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C22H21N3O3/c1-14-2-9-18(25-22(27)20-10-11-24-28-20)12-19(14)16-5-7-17(8-6-16)21(26)23-13-15-3-4-15/h2,5-12,15H,3-4,13H2,1H3,(H,23,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50262868 (CHEMBL476543 | Isoxazole-5-carboxylic acid [4'-(cy...) Show SMILES Cc1ccc(NC(=O)c2ccno2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C22H21N3O3/c1-14-2-9-18(25-22(27)20-10-11-24-28-20)12-19(14)16-5-7-17(8-6-16)21(26)23-13-15-3-4-15/h2,5-12,15H,3-4,13H2,1H3,(H,23,26)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair