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BDBM50262916 6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide 4'-[(4-methoxy-phenyl)-amide]::CHEMBL478819

SMILES: COc1ccc(NC(=O)c2ccc(cc2)-c2cc(ccc2C)C(=O)NC2CC2)cc1

InChI Key: InChIKey=MKOFLNWEPYSITR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262916   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50262916
PNG
(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)
Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2cc(ccc2C)C(=O)NC2CC2)cc1
Show InChI InChI=1S/C25H24N2O3/c1-16-3-4-19(25(29)27-20-9-10-20)15-23(16)17-5-7-18(8-6-17)24(28)26-21-11-13-22(30-2)14-12-21/h3-8,11-15,20H,9-10H2,1-2H3,(H,26,28)(H,27,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7n/an/an/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...


Bioorg Med Chem Lett 18: 4428-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.048
BindingDB Entry DOI: 10.7270/Q2CR5T5P
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50262916
PNG
(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)
Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2cc(ccc2C)C(=O)NC2CC2)cc1
Show InChI InChI=1S/C25H24N2O3/c1-16-3-4-19(25(29)27-20-9-10-20)15-23(16)17-5-7-18(8-6-17)24(28)26-21-11-13-22(30-2)14-12-21/h3-8,11-15,20H,9-10H2,1-2H3,(H,26,28)(H,27,29)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 42n/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...


Bioorg Med Chem Lett 18: 4428-32 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.048
BindingDB Entry DOI: 10.7270/Q2CR5T5P
More data for this
Ligand-Target Pair