BDBM50263050 (R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate::CHEMBL476927

SMILES: O[C@@H]1[C@@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)NC(=O)[C@@H]1O

InChI Key: InChIKey=LPEBKSIPCCGPPX-XMTFNYHQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263050 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...) Show SMILES O[C@@H]1[C@@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)NC(=O)[C@@H]1O |r| Show InChI InChI=1S/C20H21BrN2O5/c21-14-8-6-13(7-9-14)20(27)28-11-16(12-4-2-1-3-5-12)22-10-15-17(24)18(25)19(26)23-15/h1-9,15-18,22,24-25H,10-11H2,(H,23,26)/t15-,16+,17-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human LNZ308 cells				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263050 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...) Show SMILES O[C@@H]1[C@@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)NC(=O)[C@@H]1O |r| Show InChI InChI=1S/C20H21BrN2O5/c21-14-8-6-13(7-9-14)20(27)28-11-16(12-4-2-1-3-5-12)22-10-15-17(24)18(25)19(26)23-15/h1-9,15-18,22,24-25H,10-11H2,(H,23,26)/t15-,16+,17-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human HCEC				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263050 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-5-oxopyrrolidin-2...) Show SMILES O[C@@H]1[C@@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)NC(=O)[C@@H]1O |r| Show InChI InChI=1S/C20H21BrN2O5/c21-14-8-6-13(7-9-14)20(27)28-11-16(12-4-2-1-3-5-12)22-10-15-17(24)18(25)19(26)23-15/h1-9,15-18,22,24-25H,10-11H2,(H,23,26)/t15-,16+,17-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human LN18 cells				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair