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BDBM50263128 CHEMBL515318::N-[4'-(Cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-2-dimethylamino-isonicotinamide

SMILES: CN(C)c1cc(ccn1)C(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=YLBUBQKOEADWHN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263128   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50263128
PNG
(CHEMBL515318 | N-[4'-(Cyclopropylmethyl-carbamoyl)...)
Show SMILES CN(C)c1cc(ccn1)C(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1
Show InChI InChI=1S/C26H28N4O2/c1-17-4-11-22(29-26(32)21-12-13-27-24(14-21)30(2)3)15-23(17)19-7-9-20(10-8-19)25(31)28-16-18-5-6-18/h4,7-15,18H,5-6,16H2,1-3H3,(H,28,31)(H,29,32)
PDB
MMDB

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KEGG

B.MOAD
DrugBank
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
14n/an/an/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...


Bioorg Med Chem Lett 18: 4433-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.028
BindingDB Entry DOI: 10.7270/Q2JH3M0B
More data for this
Ligand-Target Pair