BDBM50263171 (+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methyl-7-azabicyclo[2.2.1]heptane::(-)-2-(6'-fluoro-3,3'-bipyridin-5-yl)-7-methyl-7-azabicyclo[2.2.1]heptane::CHEMBL478029

SMILES: CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1

InChI Key: InChIKey=PBFPUNUZLFYRGF-UHFFFAOYSA-N

Data: 7 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50263171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha2beta2 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-6 subunit (Rattus norvegicus)	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha6beta2 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha3beta2 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha2beta4 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Rattus norvegicus (Rat))	BDBM50263171 ((+)-2-(6'-[18F]fluoro-3,3'-bipyridin-5-yl)-7-methy...) Show SMILES CN1C2CCC1C(C2)c1cncc(c1)-c1ccc(F)nc1 |TLB:8:6:3.4:1| Show InChI InChI=1S/C17H18FN3/c1-21-14-3-4-16(21)15(7-14)13-6-12(8-19-9-13)11-2-5-17(18)20-10-11/h2,5-6,8-10,14-16H,3-4,7H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins UniVersity School of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cells				J Med Chem 51: 4751-64 (2008) Article DOI: 10.1021/jm800323d BindingDB Entry DOI: 10.7270/Q23N249J
					More data for this Ligand-Target Pair