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BDBM50263209 2-(Cyclopropylmethyl-amino)-N-[4'-(cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-isonicotinamide::CHEMBL478031

SMILES: Cc1ccc(NC(=O)c2ccnc(NCC3CC3)c2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=FZXJMIHXHODXER-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263209   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50263209
PNG
(2-(Cyclopropylmethyl-amino)-N-[4'-(cyclopropylmeth...)
Show SMILES Cc1ccc(NC(=O)c2ccnc(NCC3CC3)c2)cc1-c1ccc(cc1)C(=O)NCC1CC1
Show InChI InChI=1S/C28H30N4O2/c1-18-2-11-24(32-28(34)23-12-13-29-26(14-23)30-16-19-3-4-19)15-25(18)21-7-9-22(10-8-21)27(33)31-17-20-5-6-20/h2,7-15,19-20H,3-6,16-17H2,1H3,(H,29,30)(H,31,33)(H,32,34)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
6.30n/an/an/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...


Bioorg Med Chem Lett 18: 4433-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.028
BindingDB Entry DOI: 10.7270/Q2JH3M0B
More data for this
Ligand-Target Pair