BDBM50263210 CHEMBL478234::N-[4'-(Cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-2-isobutylamino-isonicotinamide

SMILES: CC(C)CNc1cc(ccn1)C(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=XUQNFBXFRVKVGS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263210 (CHEMBL478234 | N-[4'-(Cyclopropylmethyl-carbamoyl)...) Show SMILES CC(C)CNc1cc(ccn1)C(=O)Nc1ccc(C)c(c1)-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C28H32N4O2/c1-18(2)16-30-26-14-23(12-13-29-26)28(34)32-24-11-4-19(3)25(15-24)21-7-9-22(10-8-21)27(33)31-17-20-5-6-20/h4,7-15,18,20H,5-6,16-17H2,1-3H3,(H,29,30)(H,31,33)(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...				Bioorg Med Chem Lett 18: 4433-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.028 BindingDB Entry DOI: 10.7270/Q2JH3M0B
					More data for this Ligand-Target Pair