BDBM50263265 3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridin-2-yl)-N,N-diethylacrylamide::CHEMBL475918

SMILES: CCN(CC)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N

InChI Key: InChIKey=GLKZLGGCNUQEAN-RMKNXTFCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263265 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCN(CC)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C24H23N5OS/c1-4-29(5-2)22(30)9-6-17-12-19-23(16(13-25)14-27-24(19)31-17)28-20-7-8-21-18(15(20)3)10-11-26-21/h6-12,14,26H,4-5H2,1-3H3,(H,27,28)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263265 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCN(CC)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C24H23N5OS/c1-4-29(5-2)22(30)9-6-17-12-19-23(16(13-25)14-27-24(19)31-17)28-20-7-8-21-18(15(20)3)10-11-26-21/h6-12,14,26H,4-5H2,1-3H3,(H,27,28)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair