BDBM50263292 3-(4-{[3-(Diethylamino)propyl]oxy}phenyl)-2-methyl-4(3H)-quinazolinone::CHEMBL516725

SMILES: CCN(CC)CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O

InChI Key: InChIKey=UVIHFHMSMYXWGT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50263292 (3-(4-{[3-(Diethylamino)propyl]oxy}phenyl)-2-methyl...) Show SMILES CCN(CC)CCCOc1ccc(cc1)-n1c(C)nc2ccccc2c1=O Show InChI InChI=1S/C22H27N3O2/c1-4-24(5-2)15-8-16-27-19-13-11-18(12-14-19)25-17(3)23-21-10-7-6-9-20(21)22(25)26/h6-7,9-14H,4-5,8,15-16H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells				J Med Chem 51: 4780-9 (2008) Article DOI: 10.1021/jm8003834 BindingDB Entry DOI: 10.7270/Q2FQ9WFW
					More data for this Ligand-Target Pair