BDBM50263303 4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)propyl)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL476134

SMILES: Cc1c(Nc2c(cnc3sc(CCC(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12

InChI Key: InChIKey=AOEGOLJDNMUHTC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263303 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(CCC(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h5-6,8-9,12,14,26H,2-4,7,10-11H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263303 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(CCC(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h5-6,8-9,12,14,26H,2-4,7,10-11H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair