BDBM50263844 CHEMBL491614::N-methyl-4-(naphthalen-2-yl)-N-(2-(piperidin-1-yl)ethyl)piperidine-1-carboxamide

SMILES: CN(CCN1CCCCC1)C(=O)N1CCC(CC1)c1ccc2ccccc2c1

InChI Key: InChIKey=LSWHUTHYJLFYOO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50263844 (CHEMBL491614 | N-methyl-4-(naphthalen-2-yl)-N-(2-(...) Show SMILES CN(CCN1CCCCC1)C(=O)N1CCC(CC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H33N3O/c1-25(17-18-26-13-5-2-6-14-26)24(28)27-15-11-21(12-16-27)23-10-9-20-7-3-4-8-22(20)19-23/h3-4,7-10,19,21H,2,5-6,11-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 18: 5101-6 (2008) Article DOI: 10.1016/j.bmcl.2008.07.125 BindingDB Entry DOI: 10.7270/Q2PC3268
					More data for this Ligand-Target Pair