BDBM50263913 5-(3-((2H-1,2,3-triazol-2-yl)methyl)-5-(4-ethoxy-3-methylphenyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine::CHEMBL489387
SMILES: CCOc1ccc(cc1C)-c1nnc(Cn2nccn2)n1-c1ccc(OC)nc1
InChI Key: InChIKey=FMJAMEXUMLPVCZ-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxytocin receptor (Homo sapiens (Human)) | BDBM50263913 (5-(3-((2H-1,2,3-triazol-2-yl)methyl)-5-(4-ethoxy-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human oxytocin receptor by cell based beta-lactamase reporter gene assay | Bioorg Med Chem Lett 18: 5242-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.066 BindingDB Entry DOI: 10.7270/Q2833RVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50263913 (5-(3-((2H-1,2,3-triazol-2-yl)methyl)-5-(4-ethoxy-3...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human vasopressin V1a receptor by cell based beta-lactamase reporter gene assay | Bioorg Med Chem Lett 18: 5242-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.066 BindingDB Entry DOI: 10.7270/Q2833RVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50263913 (5-(3-((2H-1,2,3-triazol-2-yl)methyl)-5-(4-ethoxy-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Antagonist activity at human vasopressin V2 receptor by cell based beta-lactamase reporter gene assay | Bioorg Med Chem Lett 18: 5242-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.066 BindingDB Entry DOI: 10.7270/Q2833RVK | |||||||||||
More data for this Ligand-Target Pair |