BDBM50263950 CHEMBL490612::N-methyl-4-phenyl-N-(2-(piperidin-1-yl)ethyl)piperazine-1-carboxamide

SMILES: CN(CCN1CCCCC1)C(=O)N1CCN(CC1)c1ccccc1

InChI Key: InChIKey=HQWYGWNOAALAQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50263950 (CHEMBL490612 | N-methyl-4-phenyl-N-(2-(piperidin-1...) Show SMILES CN(CCN1CCCCC1)C(=O)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C19H30N4O/c1-20(12-13-21-10-6-3-7-11-21)19(24)23-16-14-22(15-17-23)18-8-4-2-5-9-18/h2,4-5,8-9H,3,6-7,10-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	506	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of (R)-alpha-methylhistamine-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 18: 5101-6 (2008) Article DOI: 10.1016/j.bmcl.2008.07.125 BindingDB Entry DOI: 10.7270/Q2PC3268
					More data for this Ligand-Target Pair