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BDBM50264047 2-methoxy-4-(2-(5-methoxybenzofuran-2-yl)vinyl)-N,N-dimethylbenzenamine::CHEMBL489792

SMILES: COc1ccc2oc(\C=C\c3ccc(N(C)C)c(OC)c3)cc2c1

InChI Key: InChIKey=QQQCTWMQWZDFOG-FNORWQNLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264047   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (Human))
BDBM50264047
PNG
(2-methoxy-4-(2-(5-methoxybenzofuran-2-yl)vinyl)-N,...)
Show SMILES COc1ccc2oc(\C=C\c3ccc(N(C)C)c(OC)c3)cc2c1
Show InChI InChI=1S/C20H21NO3/c1-21(2)18-9-6-14(11-20(18)23-4)5-7-17-13-15-12-16(22-3)8-10-19(15)24-17/h5-13H,1-4H3/b7-5+
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 160n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of amyloid beta42 fibril formation by thioflavin T formation


Bioorg Med Chem Lett 18: 5591-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.111
BindingDB Entry DOI: 10.7270/Q20K29G7
More data for this
Ligand-Target Pair