BDBM50264121 3-(4-(3-cyclopropyl-6-hydroxy-2-phenylnaphthalen-1-yloxy)phenyl)acrylic acid::CHEMBL490197
SMILES: OC(=O)\C=C\c1ccc(Oc2c(-c3ccccc3)c(cc3cc(O)ccc23)C2CC2)cc1
InChI Key: InChIKey=WLCNMXHJDTTWKE-OVCLIPMQSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM50264121 (3-(4-(3-cyclopropyl-6-hydroxy-2-phenylnaphthalen-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length biotinylated human ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 18: 5075-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.121 BindingDB Entry DOI: 10.7270/Q2C53KNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50264121 (3-(4-(3-cyclopropyl-6-hydroxy-2-phenylnaphthalen-1...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length biotinylated human ERalpha by scintillation proximity assay | Bioorg Med Chem Lett 18: 5075-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.121 BindingDB Entry DOI: 10.7270/Q2C53KNF | |||||||||||
More data for this Ligand-Target Pair |