BDBM50264615 CHEMBL484677::N-(4-methoxyphenyl)-3-oxoisoindoline-4-carboxamide

SMILES: COc1ccc(NC(=O)c2cccc3CNC(=O)c23)cc1

InChI Key: InChIKey=OKFLIVSLDROEJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50264615 (CHEMBL484677 | N-(4-methoxyphenyl)-3-oxoisoindolin...) Show SMILES COc1ccc(NC(=O)c2cccc3CNC(=O)c23)cc1 Show InChI InChI=1S/C16H14N2O3/c1-21-12-7-5-11(6-8-12)18-15(19)13-4-2-3-10-9-17-16(20)14(10)13/h2-8H,9H2,1H3,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin)				Bioorg Med Chem Lett 18: 5130-3 (2008) Article DOI: 10.1016/j.bmcl.2008.07.090 BindingDB Entry DOI: 10.7270/Q2RF5TVZ
					More data for this Ligand-Target Pair