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BDBM50264722 CHEMBL484881::N-((R)-1-(5-(5-chloro-3-fluoro-2-(2-methyl-2H-tetrazol-5-yl)phenyl)-3-fluoropyridin-2-yl)ethyl)-1-hydroxy-3-oxocyclopentanecarboxamide

SMILES: C[C@@H](NC(=O)C1(O)CCC(=O)C1)c1ncc(cc1F)-c1cc(Cl)cc(F)c1-c1nnn(C)n1

InChI Key: InChIKey=ZBBWXOYIAMQXIU-KXPFFURISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264722   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))		BDBM50264722
PNG
(CHEMBL484881 | N-((R)-1-(5-(5-chloro-3-fluoro-2-(2...)
Show SMILES C[C@@H](NC(=O)C1(O)CCC(=O)C1)c1ncc(cc1F)-c1cc(Cl)cc(F)c1-c1nnn(C)n1 |r|
Show InChI InChI=1S/C21H19ClF2N6O3/c1-10(26-20(32)21(33)4-3-13(31)8-21)18-16(24)5-11(9-25-18)14-6-12(22)7-15(23)17(14)19-27-29-30(2)28-19/h5-7,9-10,33H,3-4,8H2,1-2H3,(H,26,32)/t10-,21?/m1/s1
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PC sid
UniChem

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Similars
Article
PubMed
 0.670n/an/an/an/an/an/an/an/a



Merck

Curated by ChEMBL


Assay Description
Displacement of [3H]des-arg10leu9kallidin from human bradykinin B1 receptor expressed in CHO cells by Wallac beta-plate scintillation counting

Bioorg Med Chem Lett 18: 5107-10 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.126
BindingDB Entry DOI: 10.7270/Q2GX4BCV
More data for this
Ligand-Target Pair