BDBM50265276 CHEMBL498592::N-hydroxy-4-(4-iodophenoxy)thieno[2,3-c]pyridine-2-carboxamide

SMILES: ONC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1

InChI Key: InChIKey=RSNHCVNHNTXPIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50265276 (CHEMBL498592 | N-hydroxy-4-(4-iodophenoxy)thieno[2...) Show SMILES ONC(=O)c1cc2c(Oc3ccc(I)cc3)cncc2s1 Show InChI InChI=1S/C14H9IN2O3S/c15-8-1-3-9(4-2-8)20-11-6-16-7-13-10(11)5-12(21-13)14(18)17-19/h1-7,19H,(H,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant COT by HTRF-based assay				Bioorg Med Chem Lett 18: 4952-5 (2008) Article DOI: 10.1016/j.bmcl.2008.08.037 BindingDB Entry DOI: 10.7270/Q23J3CTH
					More data for this Ligand-Target Pair