BDBM50265279 4-(biphenyl-3-yloxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridine::CHEMBL497367

SMILES: O(c1cccc(c1)-c1ccccc1)c1cncc2sc(cc12)-c1nnn[nH]1

InChI Key: InChIKey=FMENTFKZKBOLCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50265279 (4-(biphenyl-3-yloxy)-2-(2H-tetrazol-5-yl)thieno[2,...) Show SMILES O(c1cccc(c1)-c1ccccc1)c1cncc2sc(cc12)-c1nnn[nH]1 Show InChI InChI=1S/C20H13N5OS/c1-2-5-13(6-3-1)14-7-4-8-15(9-14)26-17-11-21-12-19-16(17)10-18(27-19)20-22-24-25-23-20/h1-12H,(H,22,23,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant COT by HTRF-based assay				Bioorg Med Chem Lett 18: 4952-5 (2008) Article DOI: 10.1016/j.bmcl.2008.08.037 BindingDB Entry DOI: 10.7270/Q23J3CTH
					More data for this Ligand-Target Pair