BDBM50265425 2-{4-[3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)-imidazo[1,2-a]pyridin-7-yl]piperidin-1-yl}propan-1-ol::CHEMBL523086

SMILES: Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CCCO)CC1)-c1ccc(F)cc1

InChI Key: InChIKey=HNEKQDXMUAFDAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265425 (2-{4-[3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CCCO)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H27FN6O/c26-20-4-2-18(3-5-20)23-24(21-6-10-28-25(27)29-21)32-14-9-19(16-22(32)30-23)17-7-12-31(13-8-17)11-1-15-33/h2-6,9-10,14,16-17,33H,1,7-8,11-13,15H2,(H2,27,28,29)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair