BDBM50265540 4-Hydroxy-1-methyl-3-(1-methyl-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one::CHEMBL496173

SMILES: Cn1c(nc2ccccc12)-c1c(O)c2ccccc2n(C)c1=O

InChI Key: InChIKey=ZDQDOKWXXVKASN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50265540 (4-Hydroxy-1-methyl-3-(1-methyl-1H-benzo[d]imidazol...) Show SMILES Cn1c(nc2ccccc12)-c1c(O)c2ccccc2n(C)c1=O |(-1.53,-7.9,;-1.86,-6.39,;-3.27,-5.77,;-3.11,-4.24,;-1.61,-3.91,;-.85,-2.58,;.68,-2.57,;1.46,-3.91,;.69,-5.24,;-.84,-5.24,;-4.59,-6.54,;-5.94,-5.76,;-5.95,-4.22,;-7.28,-6.55,;-8.61,-5.79,;-9.94,-6.56,;-9.94,-8.1,;-8.61,-8.87,;-7.27,-8.1,;-5.93,-8.87,;-5.93,-10.41,;-4.58,-8.09,;-3.25,-8.86,)| Show InChI InChI=1S/C18H15N3O2/c1-20-14-10-6-4-8-12(14)19-17(20)15-16(22)11-7-3-5-9-13(11)21(2)18(15)23/h3-10,22H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant FGFR1				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50265540 (4-Hydroxy-1-methyl-3-(1-methyl-1H-benzo[d]imidazol...) Show SMILES Cn1c(nc2ccccc12)-c1c(O)c2ccccc2n(C)c1=O |(-1.53,-7.9,;-1.86,-6.39,;-3.27,-5.77,;-3.11,-4.24,;-1.61,-3.91,;-.85,-2.58,;.68,-2.57,;1.46,-3.91,;.69,-5.24,;-.84,-5.24,;-4.59,-6.54,;-5.94,-5.76,;-5.95,-4.22,;-7.28,-6.55,;-8.61,-5.79,;-9.94,-6.56,;-9.94,-8.1,;-8.61,-8.87,;-7.27,-8.1,;-5.93,-8.87,;-5.93,-10.41,;-4.58,-8.09,;-3.25,-8.86,)| Show InChI InChI=1S/C18H15N3O2/c1-20-14-10-6-4-8-12(14)19-17(20)15-16(22)11-7-3-5-9-13(11)21(2)18(15)23/h3-10,22H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50265540 (4-Hydroxy-1-methyl-3-(1-methyl-1H-benzo[d]imidazol...) Show SMILES Cn1c(nc2ccccc12)-c1c(O)c2ccccc2n(C)c1=O |(-1.53,-7.9,;-1.86,-6.39,;-3.27,-5.77,;-3.11,-4.24,;-1.61,-3.91,;-.85,-2.58,;.68,-2.57,;1.46,-3.91,;.69,-5.24,;-.84,-5.24,;-4.59,-6.54,;-5.94,-5.76,;-5.95,-4.22,;-7.28,-6.55,;-8.61,-5.79,;-9.94,-6.56,;-9.94,-8.1,;-8.61,-8.87,;-7.27,-8.1,;-5.93,-8.87,;-5.93,-10.41,;-4.58,-8.09,;-3.25,-8.86,)| Show InChI InChI=1S/C18H15N3O2/c1-20-14-10-6-4-8-12(14)19-17(20)15-16(22)11-7-3-5-9-13(11)21(2)18(15)23/h3-10,22H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair