BDBM50265572 3-(1H-benzo[d]imidazol-2-yl)-4-(methylamino)quinolin-2(1H)-one::CHEMBL521552

SMILES: CNc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12

InChI Key: InChIKey=QVGVBYVGAVEJHP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50265572 (3-(1H-benzo[d]imidazol-2-yl)-4-(methylamino)quinol...) Show SMILES CNc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12 Show InChI InChI=1S/C17H14N4O/c1-18-15-10-6-2-3-7-11(10)21-17(22)14(15)16-19-12-8-4-5-9-13(12)20-16/h2-9H,1H3,(H,19,20)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50265572 (3-(1H-benzo[d]imidazol-2-yl)-4-(methylamino)quinol...) Show SMILES CNc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12 Show InChI InChI=1S/C17H14N4O/c1-18-15-10-6-2-3-7-11(10)21-17(22)14(15)16-19-12-8-4-5-9-13(12)20-16/h2-9H,1H3,(H,19,20)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50265572 (3-(1H-benzo[d]imidazol-2-yl)-4-(methylamino)quinol...) Show SMILES CNc1c(-c2nc3ccccc3[nH]2)c(=O)[nH]c2ccccc12 Show InChI InChI=1S/C17H14N4O/c1-18-15-10-6-2-3-7-11(10)21-17(22)14(15)16-19-12-8-4-5-9-13(12)20-16/h2-9H,1H3,(H,19,20)(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant FGFR1				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair