BDBM50265616 CHEMBL497183::N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,2-dihydro-3H-indol-3-ylidene]benzohydrazide

SMILES: CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12

InChI Key: InChIKey=JPFBMGPXKCTWDP-UHFFFAOYSA-N

Data: 2 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50265616 (CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:10.10| Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	89.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Binding affinity to CB2 receptor				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50265616 (CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:10.10| Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	89.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Displacement of [3H] 2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol from human CB2 receptor expressed CHO-K1 cel...				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50265616 (CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:10.10| Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50265616 (CHEMBL497183 | N'-[(3Z)-1-Hexyl-6-methoxy-2-oxo-1,...) Show SMILES CCCCCCN1C(=O)C(=NNC(=O)c2ccccc2)c2ccc(OC)cc12 |w:10.10| Show InChI InChI=1S/C22H25N3O3/c1-3-4-5-9-14-25-19-15-17(28-2)12-13-18(19)20(22(25)27)23-24-21(26)16-10-7-6-8-11-16/h6-8,10-13,15H,3-5,9,14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	88.2	n/a	n/a	n/a	n/a
The University of Texas M. D. Anderson Cancer Center Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assay				J Med Chem 52: 433-44 (2009) Article DOI: 10.1021/jm801353p BindingDB Entry DOI: 10.7270/Q20G3M2X
					More data for this Ligand-Target Pair