null

SMILES: CCS(=O)(=O)Nc1cnc2Oc3ccc(Cl)cc3CCCCOc3cc(=O)n(C)cc3-c2c1

InChI Key: InChIKey=KDSKWYPIXDDXEG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265657 (CHEMBL4075776) Show SMILES CCS(=O)(=O)Nc1cnc2Oc3ccc(Cl)cc3CCCCOc3cc(=O)n(C)cc3-c2c1 Show InChI InChI=1S/C23H24ClN3O5S/c1-3-33(29,30)26-17-11-18-19-14-27(2)22(28)12-21(19)31-9-5-4-6-15-10-16(24)7-8-20(15)32-23(18)25-13-17/h7-8,10-14,26H,3-6,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265657 (CHEMBL4075776) Show SMILES CCS(=O)(=O)Nc1cnc2Oc3ccc(Cl)cc3CCCCOc3cc(=O)n(C)cc3-c2c1 Show InChI InChI=1S/C23H24ClN3O5S/c1-3-33(29,30)26-17-11-18-19-14-27(2)22(28)12-21(19)31-9-5-4-6-15-10-16(24)7-8-20(15)32-23(18)25-13-17/h7-8,10-14,26H,3-6,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.30	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of BRD4 in human NCI-H1299 cells after 24 hrs by Bright-Glo luciferase reporter gene assay				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair