BDBM50265846 3-(2-(2-methoxy-4-(1-propylpiperidin-4-yl)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)thiophene-2-carboxamide::CHEMBL515846

SMILES: CCCN1CCC(CC1)c1ccc(Nc2nc(Nc3ccsc3C(N)=O)c3cc[nH]c3n2)c(OC)c1

InChI Key: InChIKey=MMNHSQXMGMJMBM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50265846 (3-(2-(2-methoxy-4-(1-propylpiperidin-4-yl)phenylam...) Show SMILES CCCN1CCC(CC1)c1ccc(Nc2nc(Nc3ccsc3C(N)=O)c3cc[nH]c3n2)c(OC)c1 Show InChI InChI=1S/C26H31N7O2S/c1-3-11-33-12-7-16(8-13-33)17-4-5-19(21(15-17)35-2)30-26-31-24-18(6-10-28-24)25(32-26)29-20-9-14-36-22(20)23(27)34/h4-6,9-10,14-16H,3,7-8,11-13H2,1-2H3,(H2,27,34)(H3,28,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50265846 (3-(2-(2-methoxy-4-(1-propylpiperidin-4-yl)phenylam...) Show SMILES CCCN1CCC(CC1)c1ccc(Nc2nc(Nc3ccsc3C(N)=O)c3cc[nH]c3n2)c(OC)c1 Show InChI InChI=1S/C26H31N7O2S/c1-3-11-33-12-7-16(8-13-33)17-4-5-19(21(15-17)35-2)30-26-31-24-18(6-10-28-24)25(32-26)29-20-9-14-36-22(20)23(27)34/h4-6,9-10,14-16H,3,7-8,11-13H2,1-2H3,(H2,27,34)(H3,28,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R phosphorylation by cellular assay				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair