BDBM50265872 3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-1,2,3,4-tetrahydroquinolin-7-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)picolinamide::CHEMBL458864

SMILES: COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc1nc(Nc2cccnc2C(N)=O)c2cc[nH]c2n1

InChI Key: InChIKey=AQMKAWXXYOROQF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50265872 (3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-1,2,3,...) Show SMILES COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc1nc(Nc2cccnc2C(N)=O)c2cc[nH]c2n1 Show InChI InChI=1S/C26H29N9O3/c1-34(2)14-21(36)35-11-5-6-15-12-20(38-3)18(13-19(15)35)31-26-32-24-16(8-10-29-24)25(33-26)30-17-7-4-9-28-22(17)23(27)37/h4,7-10,12-13H,5-6,11,14H2,1-3H3,(H2,27,37)(H3,29,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R phosphorylation by cellular assay				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50265872 (3-(2-(1-(2-(dimethylamino)acetyl)-6-methoxy-1,2,3,...) Show SMILES COc1cc2CCCN(C(=O)CN(C)C)c2cc1Nc1nc(Nc2cccnc2C(N)=O)c2cc[nH]c2n1 Show InChI InChI=1S/C26H29N9O3/c1-34(2)14-21(36)35-11-5-6-15-12-20(38-3)18(13-19(15)35)31-26-32-24-16(8-10-29-24)25(33-26)30-17-7-4-9-28-22(17)23(27)37/h4,7-10,12-13H,5-6,11,14H2,1-3H3,(H2,27,37)(H3,29,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair