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SMILES: Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O

InChI Key: InChIKey=HTAFDYZRIYQJFP-SJORKVTESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50265896 (CHEMBL4070359) Show SMILES Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O |r| Show InChI InChI=1S/C23H19FN4O2/c1-12-3-6-22(26-10-12)28-21-9-20(25-11-18(21)13(2)27-28)15-5-4-14(7-19(15)24)16-8-17(16)23(29)30/h3-7,9-11,16-17H,8H2,1-2H3,(H,29,30)/t16-,17+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of Adenosine A2A receptor (unknown origin)				J Med Chem 60: 3187-3197 (2017) Article DOI: 10.1021/acs.jmedchem.7b00210 BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Mus musculus)	BDBM50265896 (CHEMBL4070359) Show SMILES Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O |r| Show InChI InChI=1S/C23H19FN4O2/c1-12-3-6-22(26-10-12)28-21-9-20(25-11-18(21)13(2)27-28)15-5-4-14(7-19(15)24)16-8-17(16)23(29)30/h3-7,9-11,16-17H,8H2,1-2H3,(H,29,30)/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLI...				J Med Chem 60: 3187-3197 (2017) Article DOI: 10.1021/acs.jmedchem.7b00210 BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50265896 (CHEMBL4070359) Show SMILES Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O |r| Show InChI InChI=1S/C23H19FN4O2/c1-12-3-6-22(26-10-12)28-21-9-20(25-11-18(21)13(2)27-28)15-5-4-14(7-19(15)24)16-8-17(16)23(29)30/h3-7,9-11,16-17H,8H2,1-2H3,(H,29,30)/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay				J Med Chem 60: 3187-3197 (2017) Article DOI: 10.1021/acs.jmedchem.7b00210 BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Mus musculus)	BDBM50265896 (CHEMBL4070359) Show SMILES Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O |r| Show InChI InChI=1S/C23H19FN4O2/c1-12-3-6-22(26-10-12)28-21-9-20(25-11-18(21)13(2)27-28)15-5-4-14(7-19(15)24)16-8-17(16)23(29)30/h3-7,9-11,16-17H,8H2,1-2H3,(H,29,30)/t16-,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at mouse GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assay				J Med Chem 60: 3187-3197 (2017) Article DOI: 10.1021/acs.jmedchem.7b00210 BindingDB Entry DOI: 10.7270/Q2PZ5C9Z
					More data for this Ligand-Target Pair