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SMILES: CNCC1(CC1)c1ccc(cc1)N1CCc2c(nn(c2C1=O)-c1ccc(OC)cc1)C#N

InChI Key: InChIKey=BDUIPRZETCZQER-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265978   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50265978
PNG
(1-(4-methoxyphenyl)-6-(4-(1-((methylamino)methyl)c...)
Show SMILES CNCC1(CC1)c1ccc(cc1)N1CCc2c(nn(c2C1=O)-c1ccc(OC)cc1)C#N
Show InChI InChI=1S/C25H25N5O2/c1-27-16-25(12-13-25)17-3-5-18(6-4-17)29-14-11-21-22(15-26)28-30(23(21)24(29)31)19-7-9-20(32-2)10-8-19/h3-10,27H,11-14,16H2,1-2H3
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MMDB

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Similars
Article
PubMed
 0.150n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Binding affinity to human coagulation factor 10a

Bioorg Med Chem Lett 19: 462-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.049
BindingDB Entry DOI: 10.7270/Q2M908HB
More data for this
Ligand-Target Pair