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SMILES: COc1ccc(cc1)-n1nc(C#N)c2CCN(C(=O)c12)c1ccc(cc1)C1(CN2CCOCC2)CC1

InChI Key: InChIKey=MQGZRCWHRHRCSR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266050   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50266050
PNG
(1-(4-methoxyphenyl)-6-(4-(1-(morpholinomethyl)cycl...)
Show SMILES COc1ccc(cc1)-n1nc(C#N)c2CCN(C(=O)c12)c1ccc(cc1)C1(CN2CCOCC2)CC1
Show InChI InChI=1S/C28H29N5O3/c1-35-23-8-6-22(7-9-23)33-26-24(25(18-29)30-33)10-13-32(27(26)34)21-4-2-20(3-5-21)28(11-12-28)19-31-14-16-36-17-15-31/h2-9H,10-17,19H2,1H3
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Article
PubMed
 0.0900n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Binding affinity to human coagulation factor 10a

Bioorg Med Chem Lett 19: 462-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.049
BindingDB Entry DOI: 10.7270/Q2M908HB
More data for this
Ligand-Target Pair