BDBM50266080 1-(4-methoxyphenyl)-6-(4-(1-((2-methyl-1H-imidazol-1-yl)methyl)cyclopropyl)phenyl)-3-(methylsulfonyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one 2,2,2-trifluoroacetate::CHEMBL445335

SMILES: COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(cc1)C1(Cn2ccnc2C)CC1)S(C)(=O)=O

InChI Key: InChIKey=IBWWTBSONHRQQU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50266080 (1-(4-methoxyphenyl)-6-(4-(1-((2-methyl-1H-imidazol...) Show SMILES COc1ccc(cc1)-n1nc(c2CCN(C(=O)c12)c1ccc(cc1)C1(Cn2ccnc2C)CC1)S(C)(=O)=O Show InChI InChI=1S/C28H29N5O4S/c1-19-29-15-17-31(19)18-28(13-14-28)20-4-6-21(7-5-20)32-16-12-24-25(27(32)34)33(30-26(24)38(3,35)36)22-8-10-23(37-2)11-9-22/h4-11,15,17H,12-14,16,18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to human coagulation factor 10a				Bioorg Med Chem Lett 19: 462-8 (2008) Article DOI: 10.1016/j.bmcl.2008.11.049 BindingDB Entry DOI: 10.7270/Q2M908HB
					More data for this Ligand-Target Pair