BDBM50266186 1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine::CHEMBL457984

SMILES: CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccccc3n2C)c2ccccc12

InChI Key: InChIKey=FGQULRNTICLCRF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50266186 (1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccccc3n2C)c2ccccc12 Show InChI InChI=1S/C28H23N7O/c1-29-27-31-17-15-22(32-27)20-10-7-16-30-26(20)36-25-14-13-21(18-8-3-4-9-19(18)25)33-28-34-23-11-5-6-12-24(23)35(28)2/h3-17H,1-2H3,(H,33,34)(H,29,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 19: 424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.056 BindingDB Entry DOI: 10.7270/Q29P31HK
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50266186 (1-methyl-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...) Show SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccccc3n2C)c2ccccc12 Show InChI InChI=1S/C28H23N7O/c1-29-27-31-17-15-22(32-27)20-10-7-16-30-26(20)36-25-14-13-21(18-8-3-4-9-19(18)25)33-28-34-23-11-5-6-12-24(23)35(28)2/h3-17H,1-2H3,(H,33,34)(H,29,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Tie2 (unknown origin)				Bioorg Med Chem Lett 19: 424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.056 BindingDB Entry DOI: 10.7270/Q29P31HK
					More data for this Ligand-Target Pair