BDBM50266285 CHEMBL4086276
SMILES: Cc1cc2n(C)c(=O)n(C)c2cc1N1C(=O)c2cccc3c(CCCO)ccc(C1=O)c23
InChI Key: InChIKey=OFWWWKWUCDUISA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50266285 (CHEMBL4086276) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lee Moffitt Cancer Center and Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human TAF1 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 60: 157-169 (2017) Article DOI: 10.1021/acs.jmedchem.6b00923 BindingDB Entry DOI: 10.7270/Q2TM7DMZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 1 (Homo sapiens (Human)) | BDBM50266285 (CHEMBL4086276) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lee Moffitt Cancer Center and Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant human BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assay | J Med Chem 60: 157-169 (2017) Article DOI: 10.1021/acs.jmedchem.6b00923 BindingDB Entry DOI: 10.7270/Q2TM7DMZ | |||||||||||
More data for this Ligand-Target Pair |