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SMILES: Cc1cncc(n1)-c1cc2n(ccc2cn1)-c1cccc(n1)N1CCCNCC1

InChI Key: InChIKey=GFWDUDFEFKZZQI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50266627 (CHEMBL4070117) Show SMILES Cc1cncc(n1)-c1cc2n(ccc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)18-12-20-17(14-25-18)6-10-29(20)22-5-2-4-21(27-22)28-9-3-7-23-8-11-28/h2,4-6,10,12-15,23H,3,7-9,11H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50266627 (CHEMBL4070117) Show SMILES Cc1cncc(n1)-c1cc2n(ccc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)18-12-20-17(14-25-18)6-10-29(20)22-5-2-4-21(27-22)28-9-3-7-23-8-11-28/h2,4-6,10,12-15,23H,3,7-9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50266627 (CHEMBL4070117) Show SMILES Cc1cncc(n1)-c1cc2n(ccc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)18-12-20-17(14-25-18)6-10-29(20)22-5-2-4-21(27-22)28-9-3-7-23-8-11-28/h2,4-6,10,12-15,23H,3,7-9,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair