BDBM50266629 CHEMBL4061456

SMILES: Cc1cncc(n1)-c1cn2c(ncc2cn1)-c1cccc(n1)N1CCCNCC1

InChI Key: InChIKey=NIRPQZMBABINPZ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50266629 (CHEMBL4061456) Show SMILES Cc1cncc(n1)-c1cn2c(ncc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C21H22N8/c1-15-10-23-13-18(26-15)19-14-29-16(11-24-19)12-25-21(29)17-4-2-5-20(27-17)28-8-3-6-22-7-9-28/h2,4-5,10-14,22H,3,6-9H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50266629 (CHEMBL4061456) Show SMILES Cc1cncc(n1)-c1cn2c(ncc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C21H22N8/c1-15-10-23-13-18(26-15)19-14-29-16(11-24-19)12-25-21(29)17-4-2-5-20(27-17)28-8-3-6-22-7-9-28/h2,4-5,10-14,22H,3,6-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50266629 (CHEMBL4061456) Show SMILES Cc1cncc(n1)-c1cn2c(ncc2cn1)-c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C21H22N8/c1-15-10-23-13-18(26-15)19-14-29-16(11-24-19)12-25-21(29)17-4-2-5-20(27-17)28-8-3-6-22-7-9-28/h2,4-5,10-14,22H,3,6-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair