BDBM50266642 CHEMBL4097308

SMILES: Cc1cncc(n1)-c1ccc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1

InChI Key: InChIKey=VDBZBBXSPQNDOH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50266642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50266642 (CHEMBL4097308) Show SMILES Cc1cncc(n1)-c1ccc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)17-6-7-18-14-25-29(20(18)12-17)22-5-2-4-21(27-22)28-10-3-8-23-9-11-28/h2,4-7,12-15,23H,3,8-11H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50266642 (CHEMBL4097308) Show SMILES Cc1cncc(n1)-c1ccc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)17-6-7-18-14-25-29(20(18)12-17)22-5-2-4-21(27-22)28-10-3-8-23-9-11-28/h2,4-7,12-15,23H,3,8-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50266642 (CHEMBL4097308) Show SMILES Cc1cncc(n1)-c1ccc2cnn(-c3cccc(n3)N3CCCNCC3)c2c1 Show InChI InChI=1S/C22H23N7/c1-16-13-24-15-19(26-16)17-6-7-18-14-25-29(20(18)12-17)22-5-2-4-21(27-22)28-10-3-8-23-9-11-28/h2,4-7,12-15,23H,3,8-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...				J Med Chem 60: 4458-4473 (2017) Article DOI: 10.1021/acs.jmedchem.7b00418 BindingDB Entry DOI: 10.7270/Q2H997PN
					More data for this Ligand-Target Pair