BDBM50266742 (2R,4S)-N1-(4-Chlorophenyl)-4-hydroxy-N2-(5-(2-oxopyridin-1(2H)-yl)pyridin-2-yl)-4-phenylpyrrolidine-1,2-dicarboxamide::CHEMBL515147

SMILES: O[C@@]1(C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cn1)-n1ccccc1=O)c1ccccc1

InChI Key: InChIKey=ZKLOTLQAGNYORV-QDPGVEIFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50266742 ((2R,4S)-N1-(4-Chlorophenyl)-4-hydroxy-N2-(5-(2-oxo...) Show SMILES O[C@@]1(C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cn1)-n1ccccc1=O)c1ccccc1 |r| Show InChI InChI=1S/C28H24ClN5O4/c29-20-9-11-21(12-10-20)31-27(37)34-18-28(38,19-6-2-1-3-7-19)16-23(34)26(36)32-24-14-13-22(17-30-24)33-15-5-4-8-25(33)35/h1-15,17,23,38H,16,18H2,(H,31,37)(H,30,32,36)/t23-,28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human Factor-10a				Bioorg Med Chem 17: 2501-11 (2009) Article DOI: 10.1016/j.bmc.2009.01.063 BindingDB Entry DOI: 10.7270/Q2RX9BXD
					More data for this Ligand-Target Pair