BDBM50266892 (2R,4R)-N1-(4-Chlorophenyl)-4-ethyl-N2-(2-fluoro-4-(3-methyl-2-oxopyridin-1(2H)-yl)phenyl)-4-hydroxypyrrolidine-1,2-dicarboxamide::CHEMBL515156

SMILES: CC[C@@]1(O)C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1F)-n1cccc(C)c1=O

InChI Key: InChIKey=LSOZSNOCDGEDMN-ATIYNZHBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50266892 ((2R,4R)-N1-(4-Chlorophenyl)-4-ethyl-N2-(2-fluoro-4...) Show SMILES CC[C@@]1(O)C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1F)-n1cccc(C)c1=O |r| Show InChI InChI=1S/C26H26ClFN4O4/c1-3-26(36)14-22(32(15-26)25(35)29-18-8-6-17(27)7-9-18)23(33)30-21-11-10-19(13-20(21)28)31-12-4-5-16(2)24(31)34/h4-13,22,36H,3,14-15H2,1-2H3,(H,29,35)(H,30,33)/t22-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human Factor-10a				Bioorg Med Chem 17: 2501-11 (2009) Article DOI: 10.1016/j.bmc.2009.01.063 BindingDB Entry DOI: 10.7270/Q2RX9BXD
					More data for this Ligand-Target Pair