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SMILES: CC[C@]1(C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)OC

InChI Key: InChIKey=QVKGISUQQTYAHS-ATIYNZHBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266919   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50266919
PNG
((2R,4R)-N1-(4-Chlorophenyl)-4-ethyl-N2-(2-fluoro-4...)
Show SMILES CC[C@]1(C[C@@H](N(C1)C(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1F)-n1ccccc1=O)OC |r|
Show InChI InChI=1S/C26H26ClFN4O4/c1-3-26(36-2)15-22(32(16-26)25(35)29-18-9-7-17(27)8-10-18)24(34)30-21-12-11-19(14-20(21)28)31-13-5-4-6-23(31)33/h4-14,22H,3,15-16H2,1-2H3,(H,29,35)(H,30,34)/t22-,26-/m1/s1
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Article
PubMed
n/an/a 0.220n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human Factor-10a

Bioorg Med Chem 17: 2501-11 (2009)


Article DOI: 10.1016/j.bmc.2009.01.063
BindingDB Entry DOI: 10.7270/Q2RX9BXD
More data for this
Ligand-Target Pair