BDBM50266969 CHEMBL4093656

SMILES: Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4c3)CC2)c1Cl

InChI Key: InChIKey=JJDMYYLIPNQZQN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50266969 (CHEMBL4093656) Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4c3)CC2)c1Cl Show InChI InChI=1S/C24H26Cl2N4O/c25-20-7-5-9-22(23(20)26)30-14-12-29(13-15-30)11-4-3-10-27-24(31)19-16-18-6-1-2-8-21(18)28-17-19/h1-2,5-9,16-17H,3-4,10-15H2,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.172	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by MicroBeta microplate counting method				J Med Chem 60: 580-593 (2017) Article DOI: 10.1021/acs.jmedchem.6b01148 BindingDB Entry DOI: 10.7270/Q2PV6NVS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50266969 (CHEMBL4093656) Show SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4c3)CC2)c1Cl Show InChI InChI=1S/C24H26Cl2N4O/c25-20-7-5-9-22(23(20)26)30-14-12-29(13-15-30)11-4-3-10-27-24(31)19-16-18-6-1-2-8-21(18)28-17-19/h1-2,5-9,16-17H,3-4,10-15H2,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by MicroBeta microplate counting method				J Med Chem 60: 580-593 (2017) Article DOI: 10.1021/acs.jmedchem.6b01148 BindingDB Entry DOI: 10.7270/Q2PV6NVS
					More data for this Ligand-Target Pair