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SMILES: CCc1ccc(cc1)C1C(C(C)=O)C(=O)C(=O)N1CCc1c[nH]c2ccccc12

InChI Key: InChIKey=SJENMKYEQJVVJH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267023   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50267023
PNG
(1-(2-(1H-indol-3-yl)ethyl)-4-acetyl-5-(4-ethylphen...)
Show SMILES CCc1ccc(cc1)C1C(C(C)=O)C(=O)C(=O)N1CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C24H24N2O3/c1-3-16-8-10-17(11-9-16)22-21(15(2)27)23(28)24(29)26(22)13-12-18-14-25-20-7-5-4-6-19(18)20/h4-11,14,21-22,25H,3,12-13H2,1-2H3
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Similars
Article
PubMed
 2.10E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Pim1 expressed in insect cells by HTRF

Bioorg Med Chem Lett 19: 1512-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.005
BindingDB Entry DOI: 10.7270/Q2RF5VX8
More data for this
Ligand-Target Pair